Histone Methyltransferase DOT1L Drives Recovery of Gene Expression after a Genotoxic Attack

UV-induced DNA damage causes repression of RNA synthesis. Following the removal of DNA lesions, transcription recovery operates through a process that is not understood yet. Here we show that knocking-out of the histone methyltransferase DOT1L in mouse embryonic fibroblasts (MEF(DOT1L)) leads to a U...

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Detalles Bibliográficos
Autores principales: Oksenych, Valentyn, Zhovmer, Alexander, Ziani, Salim, Mari, Pierre-Olivier, Eberova, Jitka, Nardo, Tiziana, Stefanini, Miria, Giglia-Mari, Giuseppina, Egly, Jean-Marc, Coin, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701700/
https://www.ncbi.nlm.nih.gov/pubmed/23861670
http://dx.doi.org/10.1371/journal.pgen.1003611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701700/
https://www.ncbi.nlm.nih.gov/pubmed/23861670
http://dx.doi.org/10.1371/journal.pgen.1003611

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