Effective Blocking of the White Enhancer Requires Cooperation between Two Main Mechanisms Suggested for the Insulator Function

Chromatin insulators block the action of transcriptional enhancers when interposed between an enhancer and a promoter. In this study, we examined the role of chromatin loops formed by two unrelated insulators, gypsy and Fab-7, in their enhancer-blocking activity. To test for this activity, we select...

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Detalles Bibliográficos
Autores principales: Kyrchanova, Olga, Maksimenko, Oksana, Stakhov, Viacheslav, Ivlieva, Tatyana, Parshikov, Alexander, Studitsky, Vasily M., Georgiev, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701704/
https://www.ncbi.nlm.nih.gov/pubmed/23861668
http://dx.doi.org/10.1371/journal.pgen.1003606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701704/
https://www.ncbi.nlm.nih.gov/pubmed/23861668
http://dx.doi.org/10.1371/journal.pgen.1003606

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