DNA Methylation Impacts Gene Expression and Ensures Hypoxic Survival of Mycobacterium tuberculosis

DNA methylation regulates gene expression in many organisms. In eukaryotes, DNA methylation is associated with gene repression, while it exerts both activating and repressive effects in the Proteobacteria through largely locus-specific mechanisms. Here, we identify a critical DNA methyltransferase i...

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Detalles Bibliográficos
Autores principales: Shell, Scarlet S., Prestwich, Erin G., Baek, Seung-Hun, Shah, Rupal R., Sassetti, Christopher M., Dedon, Peter C., Fortune, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701705/
https://www.ncbi.nlm.nih.gov/pubmed/23853579
http://dx.doi.org/10.1371/journal.ppat.1003419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701705/
https://www.ncbi.nlm.nih.gov/pubmed/23853579
http://dx.doi.org/10.1371/journal.ppat.1003419

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