Myxoma Virus Protein M029 Is a Dual Function Immunomodulator that Inhibits PKR and Also Conscripts RHA/DHX9 to Promote Expanded Host Tropism and Viral Replication

Myxoma virus (MYXV)-encoded protein M029 is a member of the poxvirus E3 family of dsRNA-binding proteins that antagonize the cellular interferon signaling pathways. In order to investigate additional functions of M029, we have constructed a series of targeted M029-minus (vMyx-M029KO and vMyx-M029ID)...

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Detalles Bibliográficos
Autores principales: Rahman, Masmudur M., Liu, Jia, Chan, Winnie M., Rothenburg, Stefan, McFadden, Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701710/
https://www.ncbi.nlm.nih.gov/pubmed/23853588
http://dx.doi.org/10.1371/journal.ppat.1003465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701710/
https://www.ncbi.nlm.nih.gov/pubmed/23853588
http://dx.doi.org/10.1371/journal.ppat.1003465

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