Maintenance of Intestinal Th17 Cells and Reduced Microbial Translocation in SIV-infected Rhesus Macaques Treated with Interleukin (IL)-21

In pathogenic HIV and SIV infections of humans and rhesus macaques (RMs), preferential depletion of CD4(+) Th17 cells correlates with mucosal immune dysfunction and disease progression. Interleukin (IL)-21 promotes differentiation of Th17 cells, long-term maintenance of functional CD8(+) T cells, an...

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Detalles Bibliográficos
Autores principales: Pallikkuth, Suresh, Micci, Luca, Ende, Zachary S., Iriele, Robin I., Cervasi, Barbara, Lawson, Benton, McGary, Colleen S., Rogers, Kenneth A., Else, James G., Silvestri, Guido, Easley, Kirk, Estes, Jacob D., Villinger, Francois, Pahwa, Savita, Paiardini, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701718/
https://www.ncbi.nlm.nih.gov/pubmed/23853592
http://dx.doi.org/10.1371/journal.ppat.1003471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701718/
https://www.ncbi.nlm.nih.gov/pubmed/23853592
http://dx.doi.org/10.1371/journal.ppat.1003471

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