DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations

Segmental progeroid syndromes are groups of disorders with multiple features suggestive of accelerated aging. One subset of adult-onset progeroid syndromes, referred to as atypical Werner syndrome, is caused by mutations in the LMNA gene, which encodes a class of nuclear intermediate filaments, lami...

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Detalles Bibliográficos
Autores principales: Saha, Bidisha, Zitnik, Galynn, Johnson, Simon, Nguyen, Quyen, Risques, Rosa A., Martin, George M., Oshima, Junko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701863/
https://www.ncbi.nlm.nih.gov/pubmed/23847654
http://dx.doi.org/10.3389/fgene.2013.00129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701863/
https://www.ncbi.nlm.nih.gov/pubmed/23847654
http://dx.doi.org/10.3389/fgene.2013.00129

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