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DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations
Segmental progeroid syndromes are groups of disorders with multiple features suggestive of accelerated aging. One subset of adult-onset progeroid syndromes, referred to as atypical Werner syndrome, is caused by mutations in the LMNA gene, which encodes a class of nuclear intermediate filaments, lami...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701863/ https://www.ncbi.nlm.nih.gov/pubmed/23847654 http://dx.doi.org/10.3389/fgene.2013.00129 |