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Dopamine imbalance in Huntington's disease: a mechanism for the lack of behavioral flexibility

Dopamine (DA) plays an essential role in the control of coordinated movements. Alterations in DA balance in the striatum lead to pathological conditions such as Parkinson's and Huntington's diseases (HD). HD is a progressive, invariably fatal neurodegenerative disease caused by a genetic m...

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Detalles Bibliográficos
Autores principales: Chen, Jane Y., Wang, Elizabeth A., Cepeda, Carlos, Levine, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701870/
https://www.ncbi.nlm.nih.gov/pubmed/23847463
http://dx.doi.org/10.3389/fnins.2013.00114