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In silico investigation of the short QT syndrome, using human ventricle models incorporating electromechanical coupling

Introduction: Genetic forms of the Short QT Syndrome (SQTS) arise due to cardiac ion channel mutations leading to accelerated ventricular repolarization, arrhythmias and sudden cardiac death. Results from experimental and simulation studies suggest that changes to refractoriness and tissue vulnerabi...

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Detalles Bibliográficos
Autores principales: Adeniran, Ismail, Hancox, Jules C., Zhang, Henggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701879/
https://www.ncbi.nlm.nih.gov/pubmed/23847545
http://dx.doi.org/10.3389/fphys.2013.00166