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Therapeutic anti-tumor effect of exogenous apoptin driven by human survivin gene promoter in a lentiviral construct

INTRODUCTION: The aim of this study was to construct a lentivirus vector with survivin promoter (pSur)-driven apoptin and test its efficiency in suppressing the growth of tumor cells. MATERIAL AND METHODS: Expression cassettes with different fragments of survivin gene promoter (pSur, 161 bp, 272 bp,...

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Detalles Bibliográficos
Autores principales: Ye, Feng, Zhong, Bo, Dan, Guorong, Jiang, Fan, Sai, Yan, Zhao, Jiqing, Sun, Huiqin, Zou, Zhongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701987/
https://www.ncbi.nlm.nih.gov/pubmed/23847683
http://dx.doi.org/10.5114/aoms.2013.35423