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Therapeutic anti-tumor effect of exogenous apoptin driven by human survivin gene promoter in a lentiviral construct
INTRODUCTION: The aim of this study was to construct a lentivirus vector with survivin promoter (pSur)-driven apoptin and test its efficiency in suppressing the growth of tumor cells. MATERIAL AND METHODS: Expression cassettes with different fragments of survivin gene promoter (pSur, 161 bp, 272 bp,...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Termedia Publishing House
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701987/ https://www.ncbi.nlm.nih.gov/pubmed/23847683 http://dx.doi.org/10.5114/aoms.2013.35423 |