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Evidence Against Protective Role of Sex Hormone Estrogen in Cisplatin-Induced Nephrotoxicity in Ovarectomized Rat Model
BACKGROUND: Cisplatin (CP) is an effective drug in cancer therapy to treat the solid tumors, but it is accompanied with nephrotoxicity. The protective effect of estrogen in cardiovascular diseases is well-documented; but its nephron-protective effect against CP-induced nephrotoxicity is not complete...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702126/ https://www.ncbi.nlm.nih.gov/pubmed/23833437 http://dx.doi.org/10.4103/0971-6580.111568 |