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TIMP-2 modulates cancer cell transcriptional profile and enhances E-cadherin/beta-catenin complex expression in A549 lung cancer cells

Tissue Inhibitor of Metalloproteinase 2 (TIMP-2) plays an essential role in regulating matrix remodeling, cell growth, differentiation, angiogenesis and apoptosis in vitro and in vivo. We have recently shown that TIMP-2-mediated inhibition of tumor growth is independent of matrix metalloproteinase-m...

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Detalles Bibliográficos
Autores principales: Bourboulia, Dimitra, Han, HuiYing, Jensen-Taubman, Sandra, Gavil, Noah, Isaac, Biju, Wei, Beiyang, Neckers, Len, Stetler-Stevenson, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702216/
https://www.ncbi.nlm.nih.gov/pubmed/23371049