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Differential network analysis for the identification of condition-specific pathway activity and regulation
Motivation: Identification of differential expressed genes has led to countless new discoveries. However, differentially expressed genes are only a proxy for finding dysregulated pathways. The problem is to identify how the network of regulatory and physical interactions rewires in different conditi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702259/ https://www.ncbi.nlm.nih.gov/pubmed/23749957 http://dx.doi.org/10.1093/bioinformatics/btt290 |