Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis

Exome sequencing has become a powerful and effective strategy for discovery of genes underlying Mendelian disorders(1). However, use of exome sequencing to identify variants associated with complex traits has been more challenging, partly because the samples sizes needed for adequate power may be ve...

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Detalles Bibliográficos
Autores principales: Emond, Mary J, Louie, Tin, Emerson, Julia, Zhao, Wei, Mathias, Rasika A., Knowles, Michael R., Wright, Fred A., Rieder, Mark J., Tabor, Holly K., Nickerson, Debbie A., Barnes, Kathleen C., GO, Lung, Gibson, Ronald L., Bamshad, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702264/
https://www.ncbi.nlm.nih.gov/pubmed/22772370
http://dx.doi.org/10.1038/ng.2344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702264/
https://www.ncbi.nlm.nih.gov/pubmed/22772370
http://dx.doi.org/10.1038/ng.2344

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