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NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation

The intestinal mucosa undergoes a continual process of proliferation, differentiation, and apoptosis, which is regulated by multiple signaling pathways. The Wnt/β-catenin pathway has a critical role in this process. Previously, we have shown that the calcineurin-dependent nuclear factor of activated...

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Detalles Bibliográficos
Autores principales: Wang, Q, Zhou, Y, Rychahou, P, Liu, C, Weiss, H L, Evers, B M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702276/
https://www.ncbi.nlm.nih.gov/pubmed/23764852
http://dx.doi.org/10.1038/cddis.2013.202