Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species

Lon protease is a multifunction protein and operates in protein quality control and stress response pathways in mitochondria. Human Lon is upregulated under oxidative and hypoxic stresses that represent the stress phenotypes of cancer. However, little literature undertakes comprehensive and detailed...

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Detalles Bibliográficos
Autores principales: Cheng, C-W, Kuo, C-Y, Fan, C-C, Fang, W-C, Jiang, S S, Lo, Y-K, Wang, T-Y, Kao, M-C, Lee, A Y-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702277/
https://www.ncbi.nlm.nih.gov/pubmed/23788038
http://dx.doi.org/10.1038/cddis.2013.204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702277/
https://www.ncbi.nlm.nih.gov/pubmed/23788038
http://dx.doi.org/10.1038/cddis.2013.204

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