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Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition
Cellular responses to DNA damage induced by intrinsic and extrinsic genotoxic stresses are highly regulated by complex signaling pathways, such as activation of the phosphoinositide-3-kinase-like protein kinase family and their downstream genes. Disruption of these signaling pathways leads to genome...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702279/ https://www.ncbi.nlm.nih.gov/pubmed/23807228 http://dx.doi.org/10.1038/cddis.2013.227 |