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Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition

Cellular responses to DNA damage induced by intrinsic and extrinsic genotoxic stresses are highly regulated by complex signaling pathways, such as activation of the phosphoinositide-3-kinase-like protein kinase family and their downstream genes. Disruption of these signaling pathways leads to genome...

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Detalles Bibliográficos
Autores principales: Wang, J, He, J, Su, F, Ding, N, Hu, W, Yao, B, Wang, W, Zhou, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702279/
https://www.ncbi.nlm.nih.gov/pubmed/23807228
http://dx.doi.org/10.1038/cddis.2013.227