miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer

Resistance to fluoropyrimidine-based chemotherapy is the major reason for the failure of advanced colorectal cancer (CRC) treatment. The lack of ability of tumor cells to undergo apoptosis after genotoxic stress is the key contributor to this intrinsic mechanism. Mounting evidence has demonstrated t...

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Detalles Bibliográficos
Autores principales: Karaayvaz, M, Zhai, H, Ju, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702282/
https://www.ncbi.nlm.nih.gov/pubmed/23744359
http://dx.doi.org/10.1038/cddis.2013.193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702282/
https://www.ncbi.nlm.nih.gov/pubmed/23744359
http://dx.doi.org/10.1038/cddis.2013.193

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