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miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer
Resistance to fluoropyrimidine-based chemotherapy is the major reason for the failure of advanced colorectal cancer (CRC) treatment. The lack of ability of tumor cells to undergo apoptosis after genotoxic stress is the key contributor to this intrinsic mechanism. Mounting evidence has demonstrated t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702282/ https://www.ncbi.nlm.nih.gov/pubmed/23744359 http://dx.doi.org/10.1038/cddis.2013.193 |