Three-dimensional structure of Bax-mediated pores in membrane bilayers

B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) is a member of the Bcl-2 protein family having a pivotal role in triggering cell commitment to apoptosis. Bax is latent and monomeric in the cytosol but transforms into its lethal, mitochondria-embedded oligomeric form in response to cell stress,...

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Detalles Bibliográficos
Autores principales: Xu, X-P, Zhai, D, Kim, E, Swift, M, Reed, J C, Volkmann, N, Hanein, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702287/
https://www.ncbi.nlm.nih.gov/pubmed/23788040
http://dx.doi.org/10.1038/cddis.2013.210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702287/
https://www.ncbi.nlm.nih.gov/pubmed/23788040
http://dx.doi.org/10.1038/cddis.2013.210

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