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Salinomycin induces cell death via inactivation of Stat3 and downregulation of Skp2

Salinomycin has been shown to control breast cancer stem cells, although the mechanisms underlying its anticancer effects are not clear. Deregulation of cell cycle regulators play critical roles in tumorigenesis, and they have been considered as anticancer targets. In this study, we investigated sal...

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Detalles Bibliográficos
Autores principales: Koo, K H, Kim, H, Bae, Y-K, Kim, K, Park, B-K, Lee, C-H, Kim, Y-N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702291/
https://www.ncbi.nlm.nih.gov/pubmed/23807222
http://dx.doi.org/10.1038/cddis.2013.223