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Inhibition of Rac1 promotes BMP-2-induced osteoblastic differentiation

Small G proteins of the Rho family are pivotal regulators of several signaling networks. The Ras homolog family (Rho) and one of its targets, Rho-associated protein kinase (ROCK), participate in a wide variety of biological processes, including bone formation. A previous study has demonstrated that...

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Detalles Bibliográficos
Autores principales: Onishi, M, Fujita, Y, Yoshikawa, H, Yamashita, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702300/
https://www.ncbi.nlm.nih.gov/pubmed/23807227
http://dx.doi.org/10.1038/cddis.2013.226