Cargando…

Inhibition of Rac1 promotes BMP-2-induced osteoblastic differentiation

Small G proteins of the Rho family are pivotal regulators of several signaling networks. The Ras homolog family (Rho) and one of its targets, Rho-associated protein kinase (ROCK), participate in a wide variety of biological processes, including bone formation. A previous study has demonstrated that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Onishi, M, Fujita, Y, Yoshikawa, H, Yamashita, T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702300/ https://www.ncbi.nlm.nih.gov/pubmed/23807227 http://dx.doi.org/10.1038/cddis.2013.226

Ejemplares similares

Insights into the osteoblast precursor differentiation towards mature osteoblasts induced by continuous BMP-2 signaling
por: Zouani, Omar F., et al.
Publicado: (2013)

Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF
por: Fujita, Ken-ichi, et al.
Publicado: (2007)

Inhibition of Rac and ROCK Signalling Influence Osteoblast Adhesion, Differentiation and Mineralization on Titanium Topographies
por: Prowse, Paul D. H., et al.
Publicado: (2013)

PDZRN3 Negatively Regulates BMP-2–induced Osteoblast Differentiation through Inhibition of Wnt Signaling
por: Honda, Takeshi, et al.
Publicado: (2010)

2,4,5-Trimethoxyldalbergiquinol promotes osteoblastic differentiation and mineralization via the BMP and Wnt/β-catenin pathway
por: Yun, H-M, et al.
Publicado: (2015)

Gingival fibroblasts prevent BMP‐mediated osteoblastic differentiation
por: Ghuman, Mandeep S., et al.
Publicado: (2018)

Opposing TNF-α/IL-1β- and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation
por: Huang, R-L, et al.
Publicado: (2014)

BMP-2 Induced Expression of Alx3 That Is a Positive Regulator of Osteoblast Differentiation
por: Matsumoto, Takashi, et al.
Publicado: (2013)

HIF1α Promotes BMP9-Mediated Osteoblastic Differentiation and Vascularization by Interacting with CBFA1
por: Li, Yuwan, et al.
Publicado: (2022)

Protein Palmitoylation Regulates Osteoblast Differentiation through BMP-Induced Osterix Expression
por: Leong, Wai Fook, et al.
Publicado: (2009)

Low-Intensity Pulsed Ultrasound Promotes BMP9 Induced Osteoblastic Differentiation in Rat Dedifferentiated Fat Cells
por: Setoguchi, Fumiaki, et al.
Publicado: (2023)

The Rho GTPase RAC1 in Osteoblasts Controls Their Function
por: Huck, Katrin, et al.
Publicado: (2020)

TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation
por: Chen, Guiqian, et al.
Publicado: (2012)

BMP-2 Long-Term Stimulation of Human Pre-Osteoblasts Induces Osteogenic Differentiation and Promotes Transdifferentiation and Bone Remodeling Processes
por: Ingwersen, Lena-Christin, et al.
Publicado: (2022)

Marrow adipocytes inhibit the differentiation of mesenchymal stem cells into osteoblasts via suppressing BMP-signaling
por: Abdallah, Basem M.
Publicado: (2017)

Sox9 Potentiates BMP2-Induced Chondrogenic Differentiation and Inhibits BMP2-Induced Osteogenic Differentiation
por: Liao, Junyi, et al.
Publicado: (2014)

β1 integrins mediate the BMP2 dependent transcriptional control of osteoblast differentiation and osteogenesis
por: Brunner, Molly, et al.
Publicado: (2018)

Flouride Promotes Viability and Differentiation of Osteoblast-Like Saos-2 Cells Via BMP/Smads Signaling Pathway
por: Huo, Liangliang, et al.
Publicado: (2013)

Interleukin 6 promotes BMP9-induced osteoblastic differentiation through Stat3/mTORC1 in mouse embryonic fibroblasts
por: Wang, Shi-Yu, et al.
Publicado: (2023)

BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells
por: Cui, Jing, et al.
Publicado: (2018)

Overexpression of Bcl2 in Osteoblasts Inhibits Osteoblast Differentiation and Induces Osteocyte Apoptosis
por: Moriishi, Takeshi, et al.
Publicado: (2011)

Zirconium Ions Up-Regulate the BMP/SMAD Signaling Pathway and Promote the Proliferation and Differentiation of Human Osteoblasts
por: Chen, Yongjuan, et al.
Publicado: (2015)

Screening for Small Molecule Inhibitors of BMP-Induced Osteoblastic Differentiation from Indonesian Marine Invertebrates
por: Yamazaki, Hiroyuki, et al.
Publicado: (2020)

Human Non-Hypertrophic Nonunion Tissue Contains Osteoblast Lineage Cells and E-BMP-2 Activates Osteogenic and Chondrogenic Differentiation
por: Yoshikawa, Ryo, et al.
Publicado: (2022)

Establishment of Immortalized BMP2/4 Double Knock‐Out Osteoblastic Cells Is Essential for Study of Osteoblast Growth, Differentiation, and Osteogenesis
por: Wu, Li‐An, et al.
Publicado: (2015)

Expression of Concern: Sox9 Potentiates BMP2-Induced Chondrogenic Differentiation and Inhibits BMP2-Induced Osteogenic Differentiation
Publicado: (2021)

Dickkopf-1 is involved in BMP9-induced osteoblast differentiation of C3H10T1/2 mesenchymal stem cells
por: Lin, Liangbo, et al.
Publicado: (2016)

BMP-dependent synaptic development requires Abi-Abl-Rac signaling of BMP receptor macropinocytosis
por: Kim, Najin, et al.
Publicado: (2019)

Effect of Mesenchymal Stem Cells Overexpressing BMP-9 Primed with Hypoxia on BMP Targets, Osteoblast Differentiation and Bone Repair
por: Paz, Jessica Emanuella Rocha Moura, et al.
Publicado: (2023)

CTGF Promotes the Osteoblast Differentiation of Human Periodontal Ligament Stem Cells by Positively Regulating BMP2/Smad Signal Transduction
por: Yan, Shuyun, et al.
Publicado: (2022)

A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification
por: Chen, Long, et al.
Publicado: (2022)

Marine natural products that inhibit osteoclastogenesis and promote osteoblast differentiation
por: El-Desoky, Ahmed H. H., et al.
Publicado: (2022)

Unveiling novel genes upregulated by both rhBMP2 and rhBMP7 during early osteoblastic transdifferentiation of C2C12 cells
por: Bustos-Valenzuela, Juan C, et al.
Publicado: (2011)

A Receptor Tyrosine Kinase Inhibitor, Dovitinib (TKI-258), Enhances BMP-2-Induced Osteoblast Differentiation In Vitro
por: Lee, Yura, et al.
Publicado: (2016)

Peptide drugs accelerate BMP‐2‐induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling
por: Sugamori, Yasutaka, et al.
Publicado: (2016)

Osthole Stimulates Osteoblast Differentiation and Bone Formation by Activation of β-Catenin–BMP Signaling
por: Tang, De-Zhi, et al.
Publicado: (2010)

Albiflorin Promotes Osteoblast Differentiation and Healing of Rat Femoral Fractures Through Enhancing BMP-2/Smad and Wnt/β-Catenin Signaling
por: Kim, Jae-Hyun, et al.
Publicado: (2021)

Fucoidan promotes osteoblast differentiation via JNK- and ERK-dependent BMP2–Smad 1/5/8 signaling in human mesenchymal stem cells
por: Kim, Beom Su, et al.
Publicado: (2015)

The lncRNA Rhno1/miR-6979-5p/BMP2 Axis Modulates Osteoblast Differentiation
por: Xiong, Yuan, et al.
Publicado: (2020)

Spatial Segregation of BMP/Smad Signaling Affects Osteoblast Differentiation in C2C12 Cells
por: Heining, Eva, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_3juurmgpuqc3msk20c1mtp7u1f