Cargando…

Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase

The anti-malaria drug chloroquine is well known as autophagy inhibitor. Chloroquine has also been used as anti-inflammatory drugs to treat inflammatory diseases. We hypothesized that chloroquine could have a dual effect in liver ischemia/reperfusion (I/R) injury: chloroquine on the one hand could pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, H, Liu, A, Dahmen, U, Dirsch, O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702304/
https://www.ncbi.nlm.nih.gov/pubmed/23807223
http://dx.doi.org/10.1038/cddis.2013.225