ATP citrate lyase knockdown impacts cancer stem cells in vitro

ATP citrate lyase (ACL) knockdown (KD) causes tumor suppression and induces differentiation. We have previously reported that ACL KD reverses epithelial–mesenchymal transition (EMT) in lung cancer cells. Because EMT is often associated with processes that induce stemness, we hypothesized that ACL KD...

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Detalles Bibliográficos
Autores principales: Hanai, J-i, Doro, N, Seth, P, Sukhatme, V P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702307/
https://www.ncbi.nlm.nih.gov/pubmed/23807225
http://dx.doi.org/10.1038/cddis.2013.215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702307/
https://www.ncbi.nlm.nih.gov/pubmed/23807225
http://dx.doi.org/10.1038/cddis.2013.215

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