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Anti-lymphangiogenic properties of mTOR inhibitors in head and neck squamous cell carcinoma experimental models

BACKGROUND: Tumor dissemination to cervical lymph nodes via lymphatics represents the first step in the metastasis of head and neck squamous cell carcinoma (HNSCC) and is the most significant predictor of tumor recurrence decreasing survival by 50%. The lymphatic suppressing properties of mTOR inhib...

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Detalles Bibliográficos
Autores principales: Ekshyyan, Oleksandr, Moore-Medlin, Tara N, Raley, Matthew C, Sonavane, Kunal, Rong, Xiaohua, Brodt, Michael A, Abreo, Fleurette, Alexander, Jonathan Steven, Nathan, Cherie-Ann O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702388/
https://www.ncbi.nlm.nih.gov/pubmed/23815869
http://dx.doi.org/10.1186/1471-2407-13-320