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Primary CD8(+) T cells from elite suppressors effectively eliminate non-productively HIV-1 infected resting and activated CD4(+) T cells

BACKGROUND: Elite controllers or suppressors have the remarkable capacity to maintain HIV-1 plasma RNA levels below the limit of detection of clinical assays (<50 copies/mL) without therapy and have a lower frequency of latently infected cells compared to chronic progressors. While it is unclear...

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Detalles Bibliográficos
Autores principales: Buckheit, Robert W, Siliciano, Robert F, Blankson, Joel N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702406/
https://www.ncbi.nlm.nih.gov/pubmed/23816179
http://dx.doi.org/10.1186/1742-4690-10-68