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Profiling of normal and malignant breast tissue show CD44(high)/CD24(low) phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers

BACKGROUND: Accumulating evidence supports cancer to initiate and develop from a small population of stem-like cells termed as cancer stem cells (CSC). The exact phenotype of CSC and their counterparts in normal mammary gland is not well characterized. In this study our aim was to evaluate the pheno...

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Detalles Bibliográficos
Autores principales: Ghebeh, Hazem, Sleiman, Ghida Majed, Manogaran, Pulicat S, Al-Mazrou, Amer, Barhoush, Eman, Al-Mohanna, Falah H, Tulbah, Asma, Al-Faqeeh, Khalid, Adra, Chaker N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702414/
https://www.ncbi.nlm.nih.gov/pubmed/23768049
http://dx.doi.org/10.1186/1471-2407-13-289