Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model

BACKGROUND: Parameter estimation from experimental data is critical for mathematical modeling of protein regulatory networks. For realistic networks with dozens of species and reactions, parameter estimation is an especially challenging task. In this study, we present an approach for parameter estim...

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Detalles Bibliográficos
Autores principales: Oguz, Cihan, Laomettachit, Teeraphan, Chen, Katherine C, Watson, Layne T, Baumann, William T, Tyson, John J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702416/
https://www.ncbi.nlm.nih.gov/pubmed/23809412
http://dx.doi.org/10.1186/1752-0509-7-53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702416/
https://www.ncbi.nlm.nih.gov/pubmed/23809412
http://dx.doi.org/10.1186/1752-0509-7-53

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