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Two novel PIWI families: roles in inter-genomic conflicts in bacteria and Mediator-dependent modulation of transcription in eukaryotes

BACKGROUND: The PIWI module, found in the PIWI/AGO superfamily of proteins, is a critical component of several cellular pathways including germline maintenance, chromatin organization, regulation of splicing, RNA interference, and virus suppression. It binds a guide strand which helps it target comp...

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Detalles Bibliográficos
Autores principales: Burroughs, A Maxwell, Iyer, Lakshminarayan M, Aravind, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702460/
https://www.ncbi.nlm.nih.gov/pubmed/23758928
http://dx.doi.org/10.1186/1745-6150-8-13