Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched protein tyrosine phosphatase, and homer 1, in autism: a postmortem study in cerebellar vermis and superior frontal cortex

BACKGROUND: Candidate genes associated with idiopathic forms of autism overlap with other disorders including fragile X syndrome. Our laboratory has previously shown reduction in fragile X mental retardation protein (FMRP) and increase in metabotropic glutamate receptor 5 (mGluR5) in cerebellar verm...

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Detalles Bibliográficos
Autores principales: Fatemi, S Hossein, Folsom, Timothy D, Kneeland, Rachel E, Yousefi, Mahtab K, Liesch, Stephanie B, Thuras, Paul D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702477/
https://www.ncbi.nlm.nih.gov/pubmed/23803181
http://dx.doi.org/10.1186/2040-2392-4-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702477/
https://www.ncbi.nlm.nih.gov/pubmed/23803181
http://dx.doi.org/10.1186/2040-2392-4-21

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