Cellular re- and de-programming by microenvironmental memory: why short TGF-β1 pulses can have long effects

BACKGROUND: Fibrosis poses a substantial setback in regenerative medicine. Histopathologically, fibrosis is an excessive accumulation of collagen affected by myofibroblasts and this can occur in any tissue that is exposed to chronic injury or insult. Transforming growth factor (TGF)-β1, a crucial me...

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Detalles Bibliográficos
Autores principales: Tan, Ariel Bing-Shi, Kress, Sebastian, Castro, Leticia, Sheppard, Allan, Raghunath, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702516/
https://www.ncbi.nlm.nih.gov/pubmed/23782569
http://dx.doi.org/10.1186/1755-1536-6-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702516/
https://www.ncbi.nlm.nih.gov/pubmed/23782569
http://dx.doi.org/10.1186/1755-1536-6-12

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