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Cellular re- and de-programming by microenvironmental memory: why short TGF-β1 pulses can have long effects
BACKGROUND: Fibrosis poses a substantial setback in regenerative medicine. Histopathologically, fibrosis is an excessive accumulation of collagen affected by myofibroblasts and this can occur in any tissue that is exposed to chronic injury or insult. Transforming growth factor (TGF)-β1, a crucial me...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702516/ https://www.ncbi.nlm.nih.gov/pubmed/23782569 http://dx.doi.org/10.1186/1755-1536-6-12 |