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Dual Mechanisms of Translation Initiation of the Full-Length HIV-1 mRNA Contribute to Gag Synthesis

The precursor group-specific antigen (pr55(Gag)) is central to HIV-1 assembly. Its expression alone is sufficient to assemble into virus-like particles. It also selects the genomic RNA for encapsidation and is involved in several important virus-host interactions for viral assembly and restriction,...

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Detalles Bibliográficos
Autores principales: Monette, Anne, Valiente-Echeverría, Fernando, Rivero, Matias, Cohen, Éric A., Lopez-Lastra, Marcelo, Mouland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702555/
https://www.ncbi.nlm.nih.gov/pubmed/23861855
http://dx.doi.org/10.1371/journal.pone.0068108