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Antibodies to Polymorphic Invasion-Inhibitory and Non-Inhibitory Epitopes of Plasmodium falciparum Apical Membrane Antigen 1 in Human Malaria

BACKGROUND: Antibodies to P. falciparum apical membrane protein 1 (AMA1) may contribute to protective immunity against clinical malaria by inhibiting blood stage growth of P. falciparum, and AMA1 is a leading malaria vaccine candidate. Currently, there is limited knowledge of the acquisition of stra...

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Detalles Bibliográficos
Autores principales: Mugyenyi, Cleopatra K., Elliott, Salenna R., McCallum, Fiona J., Anders, Robin F., Marsh, Kevin, Beeson, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702562/
https://www.ncbi.nlm.nih.gov/pubmed/23861883
http://dx.doi.org/10.1371/journal.pone.0068304