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Cytomegalovirus pp71 Protein Is Expressed in Human Glioblastoma and Promotes Pro-Angiogenic Signaling by Activation of Stem Cell Factor

Glioblastoma multiforme (GBM) is a highly malignant primary central nervous system neoplasm characterized by tumor cell invasion, robust angiogenesis, and a mean survival of 15 months. Human cytomegalovirus (HCMV) infection is present in >90% of GBMs, although the role the virus plays in GBM path...

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Detalles Bibliográficos
Autores principales: Matlaf, Lisa A., Harkins, Lualhati E., Bezrookove, Vladimir, Cobbs, Charles S., Soroceanu, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702580/
https://www.ncbi.nlm.nih.gov/pubmed/23861869
http://dx.doi.org/10.1371/journal.pone.0068176