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Effects of Sodium Butyrate and Its Synthetic Amide Derivative on Liver Inflammation and Glucose Tolerance in an Animal Model of Steatosis Induced by High Fat Diet

BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease. Insulin resistance (IR) appears to be critical in its pathogenesis. We evaluated the effects of sodium butyrate (butyrate) and its synthetic derivative N-(1-carbamoyl-2-phenyl-ethyl) but...

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Detalles Bibliográficos
Autores principales: Mattace Raso, Giuseppina, Simeoli, Raffaele, Russo, Roberto, Iacono, Anna, Santoro, Anna, Paciello, Orlando, Ferrante, Maria Carmela, Canani, Roberto Berni, Calignano, Antonio, Meli, Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702592/
https://www.ncbi.nlm.nih.gov/pubmed/23861927
http://dx.doi.org/10.1371/journal.pone.0068626