Redox Signaling via Oxidative Inactivation of PTEN Modulates Pressure-Dependent Myogenic Tone in Rat Middle Cerebral Arteries

The present study examined the level of generation of reactive oxygen species (ROS) and roles of inactivation of the phosphatase PTEN and the PI3K/Akt signaling pathway in response to an increase in intramural pressure-induced myogenic cerebral arterial constriction. Step increases in intraluminal p...

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Detalles Bibliográficos
Autores principales: Gebremedhin, Debebe, Terashvili, Maia, Wickramasekera, Nadi, Zhang, David X., Rau, Nicole, Miura, Hiroto, Harder, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702596/
https://www.ncbi.nlm.nih.gov/pubmed/23861911
http://dx.doi.org/10.1371/journal.pone.0068498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702596/
https://www.ncbi.nlm.nih.gov/pubmed/23861911
http://dx.doi.org/10.1371/journal.pone.0068498

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