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The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

Glucocorticoid receptor binds to genomic response elements and regulates gene transcription with cell- and gene-specificity. Within a response element, the precise sequence to which the receptor binds has been implicated in directing its structure and activity. We use NMR chemical shift difference m...

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Detalles Bibliográficos
Autores principales: Watson, Lisa C., Kuchenbecker, Kristopher M., Schiller, Benjamin J., Gross, John D., Pufall, Miles A., Yamamoto, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702670/
https://www.ncbi.nlm.nih.gov/pubmed/23728292
http://dx.doi.org/10.1038/nsmb.2595