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Re-emergence of interferon-α in the treatment of chronic myeloid leukemia

Treatment for chronic myeloid leukemia (CML) has evolved from chemotherapy (busulfan, hydroxyurea) to interferon-α (IFNα), and finally to tyrosine kinase inhibitors such as imatinib. Although imatinib has profoundly improved outcomes for patients with CML, it has limitations. Most significantly, ima...

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Detalles Bibliográficos
Autores principales: Talpaz, M, Hehlmann, R, Quintás-Cardama, A, Mercer, J, Cortes, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703612/
https://www.ncbi.nlm.nih.gov/pubmed/23238589
http://dx.doi.org/10.1038/leu.2012.313