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Selective Nucleic Acid Capture with Shielded Covalent Probes

[Image: see text] Nucleic acid probes are used for diverse applications in vitro, in situ, and in vivo. In any setting, their power is limited by imperfect selectivity (binding of undesired targets) and incomplete affinity (binding is reversible, and not all desired targets bound). These difficultie...

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Detalles Bibliográficos
Autores principales: Vieregg, Jeffrey R., Nelson, Hosea M., Stoltz, Brian M., Pierce, Niles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703666/
https://www.ncbi.nlm.nih.gov/pubmed/23745667
http://dx.doi.org/10.1021/ja4009216