Discovery of Small-Molecule Modulators of the Sonic Hedgehog Pathway

[Image: see text] The Hedgehog signaling pathway is involved in the development of multicellular organisms and, when deregulated, can contribute to certain cancers, among other diseases. The molecular characterization of the pathway, which has been enabled by small-molecule probes targeting its comp...

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Detalles Bibliográficos
Autores principales: Schaefer, Giannina I., Perez, José R., Duvall, Jeremy R., Stanton, Benjamin Z., Shamji, Alykhan F., Schreiber, Stuart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703668/
https://www.ncbi.nlm.nih.gov/pubmed/23725514
http://dx.doi.org/10.1021/ja400034k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703668/
https://www.ncbi.nlm.nih.gov/pubmed/23725514
http://dx.doi.org/10.1021/ja400034k

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