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Inside job: ligand-receptor pharmacology beneath the plasma membrane
Most drugs acting on the cell surface receptors are membrane permeable and thus able to engage their target proteins in different subcellular compartments. However, these drugs' effects on cell surface receptors have historically been studied on the plasma membrane alone. Increasing evidence su...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703709/ https://www.ncbi.nlm.nih.gov/pubmed/23685953 http://dx.doi.org/10.1038/aps.2013.51 |