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Inside job: ligand-receptor pharmacology beneath the plasma membrane

Most drugs acting on the cell surface receptors are membrane permeable and thus able to engage their target proteins in different subcellular compartments. However, these drugs' effects on cell surface receptors have historically been studied on the plasma membrane alone. Increasing evidence su...

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Detalles Bibliográficos
Autores principales: Babcock, Joseph J, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703709/
https://www.ncbi.nlm.nih.gov/pubmed/23685953
http://dx.doi.org/10.1038/aps.2013.51