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Unlipidated Outer Membrane Protein Omp16 (U-Omp16) from Brucella spp. as Nasal Adjuvant Induces a Th1 Immune Response and Modulates the Th2 Allergic Response to Cow’s Milk Proteins

The discovery of novel mucosal adjuvants will help to develop new formulations to control infectious and allergic diseases. In this work we demonstrate that U-Omp16 from Brucella spp. delivered by the nasal route (i.n.) induced an inflammatory immune response in bronchoalveolar lavage (BAL) and lung...

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Detalles Bibliográficos
Autores principales: Ibañez, Andrés E., Smaldini, Paola, Coria, Lorena M., Delpino, María V., Pacífico, Lucila G. G., Oliveira, Sergio C., Risso, Gabriela S., Pasquevich, Karina A., Fossati, Carlos Alberto, Giambartolomei, Guillermo H., Docena, Guillermo H., Cassataro, Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703917/
https://www.ncbi.nlm.nih.gov/pubmed/23861971
http://dx.doi.org/10.1371/journal.pone.0069438