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Unlipidated Outer Membrane Protein Omp16 (U-Omp16) from Brucella spp. as Nasal Adjuvant Induces a Th1 Immune Response and Modulates the Th2 Allergic Response to Cow’s Milk Proteins
The discovery of novel mucosal adjuvants will help to develop new formulations to control infectious and allergic diseases. In this work we demonstrate that U-Omp16 from Brucella spp. delivered by the nasal route (i.n.) induced an inflammatory immune response in bronchoalveolar lavage (BAL) and lung...
Autores principales: | Ibañez, Andrés E., Smaldini, Paola, Coria, Lorena M., Delpino, María V., Pacífico, Lucila G. G., Oliveira, Sergio C., Risso, Gabriela S., Pasquevich, Karina A., Fossati, Carlos Alberto, Giambartolomei, Guillermo H., Docena, Guillermo H., Cassataro, Juliana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703917/ https://www.ncbi.nlm.nih.gov/pubmed/23861971 http://dx.doi.org/10.1371/journal.pone.0069438 |
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