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Optically Induced Thermal Gradients for Protein Characterization in Nanolitre-scale Samples in Microfluidic Devices

Proteins are the most vital biological functional units in every living cell. Measurement of protein stability is central to understanding their structure, function and role in diseases. While proteins are also sought as therapeutic agents, they can cause diseases by misfolding and aggregation in vi...

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Detalles Bibliográficos
Autores principales: Sagar, D. M., Aoudjane, Samir, Gaudet, Matthieu, Aeppli, Gabriel, Dalby, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703920/
https://www.ncbi.nlm.nih.gov/pubmed/23823279
http://dx.doi.org/10.1038/srep02130