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Probabilistic models for CRISPR spacer content evolution

BACKGROUND: The CRISPR/Cas system is known to act as an adaptive and heritable immune system in Eubacteria and Archaea. Immunity is encoded in an array of spacer sequences. Each spacer can provide specific immunity to invasive elements that carry the same or a similar sequence. Even in closely relat...

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Detalles Bibliográficos
Autores principales: Kupczok, Anne, Bollback, Jonathan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704272/
https://www.ncbi.nlm.nih.gov/pubmed/23442002
http://dx.doi.org/10.1186/1471-2148-13-54