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Hyaluronan–cisplatin conjugate nanoparticles embedded in Eudragit S100-coated pectin/alginate microbeads for colon drug delivery

Hyaluronan–cisplatin conjugate nanoparticles (HCNPs) were chosen as colon-targeting drug-delivery carriers due to the observation that a variety of malignant tumors overexpress hyaluronan receptors. HCNPs were prepared by mixing cisplatin with a hyaluronan solution, followed by dialysis to remove tr...

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Detalles Bibliográficos
Autores principales: Tsai, Shiao-Wen, Yu, Ding-Syuan, Tsao, Shu-Wei, Hsu, Fu-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704403/
https://www.ncbi.nlm.nih.gov/pubmed/23861585
http://dx.doi.org/10.2147/IJN.S46613