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Catalytic-independent roles of UTX-1 in C. elegans development

We recently analyzed the functional roles of UTX-1 during development. utx-1 is an essential gene required for the correct embryonic and post-embryonic development of C. elegans, and it displays an H3K27me3 demethylase activity. Rescue experiments demonstrated that the enzymatic activity of UTX-1 is...

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Detalles Bibliográficos
Autores principales: Vandamme, Julien, Salcini, Anna Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704440/
https://www.ncbi.nlm.nih.gov/pubmed/24058866
http://dx.doi.org/10.4161/worm.22188